As early as the 15th century, medical scholars in Far Eastern cultures such as China relied on products rich in vitamin A to treat patients with night blindness. At that time, however, it was not yet known that the active ingredient contained the said vitamin. Rather, the physicians believed in the positive power of the food used. Its effectiveness has been confirmed several times and, from the 20th century onwards, led to the healthcare sector taking a closer look at the connection between diets, i.e. the conscious withdrawal of some nutrients, and an improvement in general condition.
This resulted in the finding that a lack of essential fatty acids promotes long-term growth problems, but this has only been tested in relation to mammals. It was only when Thomas Burr Osborne, Lafayette Benedict Mendel and Elmer McCollum successfully isolated the essential retinol (often referred to as vitamin A) in 1913 that researchers and physicians recognized the actual dependence of the organism on certain vitamins and thus also on the vitamin A
In the course of this, the various vitamins were categorized in 1916 and subsequently in 1920 they were named vitamin A for the first time to use health.