The vitamin was first identified in 1922 when Catherine S. Bishop and Herbert M. Evans discovered it. At that time, the two American researchers recognized that an unknown fat-soluble factor was necessary for reproduction in rodents such as rats and subsequently discovered vitamin E.
It is not for nothing that this substance is also called the fertility vitamin. In the years to come, scientists isolated the factor primarily from corn, wheat germ oils or oats and named it vitamin E. The basis was the long-established vitamins A, B, C and D, so that vitamin E as a designation was nothing more than the logical order in the vitamin chain. In 1938, the structure of the vitamin was deciphered and the first chemical synthesis was carried out.
These were initially the tocotrienols, which were synthesized in 1956. To date, vitamin E exists as a synthetic product and as a natural vitamin, with the synthetic variant having reduced potency.